COMPATIBILITY STUDIES OF SELECTED MUCOLYTIC DRUGS WITH EXCIPIENTS USED IN SOLID DOSAGE FORMS: THERMOGRAVIMETRY ANALYSIS
نویسندگان
چکیده
منابع مشابه
Thermal behaviour of procaine and benzocaine Part II: compatibility study with some pharmaceutical excipients used in solid dosage forms
BACKGROUND The compatibility study of active substances with excipients finds an important role in the domain of pharmaceutical research, being known the fact that final formulation is the one administered to the patient. In order to evaluate the compatibility between active substance and excipients, different analytical techniques can be used, based on their accuracy, reproducibility and fastn...
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FELICIA DRAGAN1, IRINA KACSO2, FLAVIA MARTIN2*, GHEORGHE BORODI2, IOAN BRATU2, MARCEL COSTULEANU3, IOAN GABRIEL SANDU4,5*, VLADIMIR POROCH6,7 1 Oradea University, Faculty of Medicine and Pharmacy, 1 Armatei Romane Str., 410087, Oradea, Romania 2 National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Str., 400293, Cluj Napoca, Romania, 3 Grigore T. P...
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Experiments were done to assess the compatibility of nateglinide with selected excipients in the development of immediate release tablets of nateglinide by thermal and isothermal stress testing (IST) techniques. To evaluate the drug-excipient compatibility, different techniques such as differential scanning calorimetric (DSC) study, infra-red (IR) spectrophotometric study and isothermal stress ...
متن کاملCharacterization and Evaluation of Spray Dried Co- Processed Excipients and Their Application in Solid Dosage Forms
Major challenge for tablet manufacture comes from the powder characteristics of the materials to be compressed. This in turn poses a challenge in achieving greater productivity and better quality product especially on the new generation high-speed machines. Advancement in directly compressible materials has come in the form of co processed spray dried materials. The present work evaluates and ...
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ژورنال
عنوان ژورنال: Farmacia
سال: 2021
ISSN: ['2065-0019', '0014-8237']
DOI: https://doi.org/10.31925/farmacia.2021.3.22